原標題：樹花粉暴露與兒童肺功能下降有關(guān)
背景：過敏性疾病是一種公認的全球性流行病，是導(dǎo)致健康狀況差和生活質(zhì)量低下的重要原因?；ǚ圻^敏的流行率在世界各地都很高，花粉暴露在哮喘急診和住院治療中扮演著重要角色。肺功能和氣道炎癥是哮喘發(fā)作和控制的重要指標。
方法：本研究對一組居住在澳大利亞悉尼的高危兒童在8歲和14歲時進行肺活量測定和呼出一氧化氮（FeNO）測定。以肺功能測定當天及之前3天的環(huán)境花粉濃度作為暴露測量。住宅區(qū)的綠色度是從衛(wèi)星圖像中提取出來的。我們模擬了6種花粉類型與肺功能和FeNO的關(guān)系。我們也評估了住宅綠化的改善效果。  
結(jié)果：測量前1天和前3天空氣中的木麻黃、柏樹和松樹花粉與8歲兒童肺功能降低有關(guān)?；ǚ郾┞杜cFEV1和FVC降低有關(guān)，但FEV1/FVC比值不受影響。
結(jié)論：空氣中的柏樹、木麻黃、松樹花粉在某些地區(qū)可能不利于兒童肺功能。


延伸閱讀
Clinical & Experimental Allergy
Tree pollen exposure is associated with reduced lung function in children
DOI: 10.1111/cea.13711
Abstract:
Background: Allergic disease is a recognized global epidemic and a significant cause of ill health and poor quality of life. The prevalence of pollen allergy is high throughout the world, and pollen exposure itself plays a role in emergency department presentations and hospitalizations for asthma. Lung function and airway inflammation are important measures of asthma activity and control.
Methods: A cohort of high-risk children living in Sydney, Australia had spirometry and fractional exhaled nitric oxide (FeNO) measured at 8 and 14 years of age. Ambient pollen concentration on the day of lung function measurement and up to three days prior was used as the exposure measure. Residential greenness was derived from satellite imagery. We modelled the association between six pollen types and lung function and FeNO. We also assessed modifying effects of residential greenness.
Results: Casuarina, cypress and Pinus pollen in the air the day before measurement and 3 days prior respectively, were associated with reduced lung function in 8-yearolds. The pollen exposures were associated with decreases in FEV1 and FVC; however, the FEV1/FVC ratio was not affected. Effect modification by greenness was not observed due to loss of power.
Conclusions: Airborne tree pollen of cypress, Casuarina and Pinus and not grass in some regions may be detrimental to childhood lung function.
First Author:
Katrina A Lambert
Correspondence:
Bircan Erbas, School of Public Health, La Trobe University, Rm 129, Health Sciences 1, Bundoora, Vic. 3086, Australia.
All Authors:
Katrina A Lambert, Constance Katelaris, Pamela Burton, Christine Cowie, Caroline Lodge, Frances L Garden, Luke A Prendergast, Brett G Toelle, Bircan Erbas
2020-10-30 Article 
　　創(chuàng)建過敏性疾病的科研、科普知識交流平臺，為過敏患者提供專業(yè)診斷、治療、預(yù)防的共享平臺。